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	Provedor de dados BJMBR (4) Autor Chagas,A.C.P. (4) Dourado,P.M.M. (4) Mathias Jr.,W. (3) Tsutsui,J.M. (3) da Luz,P.L. (3) Aiello,V.D. (2) Landim,M.B.P. (2) Andrade,J.L. (1) Casella Filho,A. (1) Casella-Filho,A. (1) Galvao,T.F.G. (1) Ramires,A.F. (1) Santos,J.M.T. (1) da-Luz,P.L. (1) Mais... Palavra-chave Hypercholesterolemia (2) Acute myocardial infarction (1) Asymmetric dimethylarginine (1) Bioeffects (1) Cardiotonics (1) Contrast echocardiography (1) Microbubbles (1) Myocardial contrast echocardiography (1) Myocardial infarction (1) Myocardial necrosis (1) Myocardial perfusion (1) Myocardial stunning (1) Nitric oxide (1) Risk factors (1) Rosuvastatin (1) Ultrasound (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2013 (1) 2011 (1) 2006 (1) 2003 (1) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Bioeffects of albumin-encapsulated microbubbles and real-time myocardial contrast echocardiography in an experimental canine model BJMBR Dourado,P.M.M.; Tsutsui,J.M.; Santos,J.M.T.; Aiello,V.D.; Mathias Jr.,W.; Ramires,A.F.; da Luz,P.L.; Chagas,A.C.P.. Myocardial contrast echocardiography has been used for assessing myocardial perfusion. Some concerns regarding its safety still remain, mainly regarding the induction of microvascular alterations. We sought to determine the bioeffects of microbubbles and real-time myocardial contrast echocardiography (RTMCE) in a closed-chest canine model. Eighteen mongrel dogs were randomly assigned to two groups. Nine were submitted to continuous intravenous infusion of perfluorocarbon-exposed sonicated dextrose albumin (PESDA) plus continuous imaging using power pulse inversion RTMCE for 180 min, associated with manually deflagrated high-mechanical index impulses. The control group consisted of 3 dogs submitted to continuous imaging using RTMCE without PESDA, 3 dogs... Tipo: Info:eu-repo/semantics/article Palavras-chave: Microbubbles; Ultrasound; Bioeffects; Myocardial contrast echocardiography. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600017 Evaluation of stunned and infarcted canine myocardium by real time myocardial contrast echocardiography BJMBR Dourado,P.M.M.; Tsutsui,J.M.; Mathias Jr.,W.; Andrade,J.L.; da Luz,P.L.; Chagas,A.C.P.. Differentiation between stunned and infarcted myocardium in the setting of acute ischemia is challenging. Real time myocardial contrast echocardiography allows the simultaneous assessment of myocardial perfusion and function. In the present study we evaluated infarcted and stunned myocardium in an experimental model using real time myocardial contrast echocardiography. Sixteen dogs underwent 180 min of coronary occlusion followed by reperfusion (infarct model) and seven other dogs were submitted to 20 min of coronary occlusion followed by reperfusion (stunned model). Wall motion abnormality and perfusional myocardial defect areas were measured by planimetry. Risk and infarct areas were determined by tissue staining. In the infarct model, the wall motion... Tipo: Info:eu-repo/semantics/article Palavras-chave: Myocardial perfusion; Contrast echocardiography; Myocardial stunning; Myocardial infarction. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001100009 High plasma concentrations of asymmetric dimethylarginine inhibit ischemic cardioprotection in hypercholesterolemic rats BJMBR Landim,M.B.P.; Dourado,P.M.M.; Casella-Filho,A.; Chagas,A.C.P.; da-Luz,P.L.. A low concentration of nitric oxide associated with a high concentration of asymmetric dimethylarginine (ADMA) can explain the lack of ischemic cardioprotection observed in the presence of hypercholesterolemia. The objective of the present study was to evaluate the effect of hypercholesterolemia on ischemic pre- and postconditioning and its correlation with plasma concentrations of ADMA. Male Wistar rats (6-8 weeks old) fed a 2% cholesterol diet (n = 21) for 8 weeks were compared to controls (n = 25) and were subjected to experimental myocardial infarction and reperfusion, with ischemic pre- and postconditioning. Total cholesterol and ADMA were measured in plasma before the experimental infarct and the infarct area was quantified. Weight, total cholesterol... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypercholesterolemia; Cardiotonics; Nitric oxide; Risk factors; Asymmetric dimethylarginine. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000500454 Rosuvastatin prevents myocardial necrosis in an experimental model of acute myocardial infarction BJMBR Dourado,P.M.M.; Tsutsui,J.M.; Landim,M.B.P.; Casella Filho,A.; Galvao,T.F.G.; Aiello,V.D.; Mathias Jr.,W.; da Luz,P.L.; Chagas,A.C.P.. Dyslipidemia is related to the progression of atherosclerosis and is an important risk factor for acute coronary syndromes. Our objective was to determine the effect of rosuvastatin on myocardial necrosis in an experimental model of acute myocardial infarction (AMI). Male Wistar rats (8-10 weeks old, 250-350 g) were subjected to definitive occlusion of the left anterior descending coronary artery to cause AMI. Animals were divided into 6 groups of 8 to 11 rats per group: G1, normocholesterolemic diet; G2, normocholesterolemic diet and rosuvastatin (1 mg·kg-1·day-1) 30 days after AMI; G3, normocholesterolemic diet and rosuvastatin (1 mg·kg-1·day-1) 30 days before and after AMI; G4, hypercholesterolemic diet; G5, hypercholesterolemic diet and rosuvastatin (1... Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute myocardial infarction; Rosuvastatin; Hypercholesterolemia; Myocardial necrosis. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000500013 Registros recuperados: 4 Primeira ... 1 ... Última

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